Products to Speed You to Market:
cDNA clones: synthetic target genes available for six recombinant proteins and five monoclonal antibiodies. DNA sequences were reversed translated from the amino acid sequences with convenient restriction sites introduced.
Proprietary expression cassettes: for monoclonal antibodies
Protein reference standards: cell line and process technology for preparation of protein reference standards (appropriate for US FDA)
Purification references: several purification processes for recovery of proteins derived from various hosts icluding E.coli, pichia pastoris, CHO
Analytical tools: analytical methodologies developed for characterization of complex glycosylated proteins, including preptide mappoing, n-glycan, o-glycan analysis, and cell based bioassays
Biosimilar Projects:**
Pedigreed cell lines + tech package ready now for rituximab and bevacizumab
Pedigreed cell lines + tech package ready 12/2010 for fortrastuzumab, infliximab, adalimumab, cetuximab
BioBetters: Pedigreed cell lines, process development, controlled release scaffold for dibotermin alfa BMP2
PEGylated Biosimilars: Pedigreed cell lines completed for PEG filgrastim (C-CSF) and PEG alpha interferon 2b
Commodity Biosimilars: Pedigreed cell lines completed for EPO, G-CSF, hGH
cDNA clones: completed and available for yeast vectors
Protein reference standards and Purfication references: completed and available for second generation biobetters